ISS Expedition 52 refers to the 52nd long-duration crewed flight mission aboard the International Space Station (ISS), a multinational collaborative space station in low Earth orbit. During this expedition, NASA provided crew members for the spacecraft, continuing global cooperation and scientific research. The exact duration of ISS Expedition 52 can vary but typically lasts several months. Key activities during this mission included conducting experiments in biology, physical science, technology development, Earth observation, and education outreach. This specific expedition saw NASA astronauts working alongside cosmonauts from the Russian space agency Roscosmos, as well as possibly astronauts from other international partner agencies such as ESA (European Space Agency), JAXA (Japan Aerospace Exploration Agency), and CSA (Canadian Space Agency). The primary objectives were to maintain and develop the ISS as a vital research laboratory while advancing human spaceflight capabilities.